Annual Scientific Report 2015

Abstract

Our research group works in the “OMCOS” (organometallic chemistry directed towards organic synthesis) arena, mainly on gold catalysis, with a focus on the discovery of new catalytic transformations, the understanding of their mechanisms, and the application of these catalytic reactions for the synthesis of biologically active natural products and polyarenes of importance in material science.

Topics addressed

• New gold-catalyzed reactions for the activation of alkynes
• Synthesis of biologically active natural products
• New strategies for the synthesis of polyarenes

Articles

“Towards the Ideal Synthesis of Homoallylic Ketones”
ChemCatChem (2015), 7, 228–229
Ferrer, M. E. Muratore, A.M. Echavarren

“Enantioselective Total Synthesis of (–)-Nardoaristolone B via a Gold(I)-Catalyzed Oxidative Cyclization”
Org. Lett. (2015), 17, 461–463
Homs, M. E. Muratore, A. M. Echavarren

“Gold Carbene or Carbenoid, is there a Difference?”
Chem. Eur. J. (2015), 21, 7332–7339
Wang, M. E. Muratore, A. M. Echavarren

“Tetrabenzocircumpyrene: A Nanographene Fragment with an Embedded Peripentacene Core”
Chem. Comm. (2015), 51, 6932–6935
Dorel, C. Manzano, M. Grisolia,W.-H- Soe, C. Joachim, A. M. Echavarren

“Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity”
Chem. Rev. (2015) 115, 9028–9072
Dorel, A. M. Echavarren

“Anatomy of Gold Catalysts: Facts and Myths”
Org. Bioorg. Chem. (2015), 13, 7103–7118
Ranieri, I. Escofet, A. M. Echavarren

“Gold-Catalyzed Reactions via Cyclopropyl Gold Carbene-like Intermediates”
Org. Chem. (2015), 80, 7321–7332
Dorel, A. M. Echavarren