Suero
Research group
Abstract
The major goal of the Suero Group is to develop new small molecule asymmetric activation modes and their application in solving important synthesis problems. We are exploiting single electron transfer chemistry for the catalytic generation of unusual reactive species able to evolve through unconventional C=C and C–H bond activations. Our group aims to apply the novel reactivity concepts for streamlining the synthesis of relevant bioactive molecules in diverse areas of disease but also for the development of site-selective functionalizations of biomolecules. Currently, we are developing a novel diastereoconvergent alkene cyclopropanation reaction based on the catalytic generation of novel radical carbenoids. This process employs a reactivity principle that differs from classical cyclopropanation reactions.
Topics addressed
- Development of unconventional C=C and C-H bond activations.
- Novel concepts in photoredox catalysis.
Articles
“A Diastereoconvergent Alkene Cyclopropanation Reaction with Radical Carbenoids”
Manuscript in preparation
Ana M. del Hoyo, Ana García-Herraiz, Marcos G. Suero.